2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114750R
    Mebendazole-amine (Standard)
    Mebendazole-amine (Standard) is the analytical standard of Mebendazole-amine. This product is intended for research and analytical applications. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.
    Mebendazole-amine (Standard)
  • HY-A0154R
    Deslanoside (Standard)
    Deslanoside (Standard) is the analytical standard of Deslanoside. This product is intended for research and analytical applications. Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
    Deslanoside (Standard)
  • HY-171043
    3-Hydroxy desalkylgidazepam
    3-Hydroxy desalkylgidazepam (compound 2) is the active metabolite of Gidazepam (HY-U00315) and Desalkylgidazepam (HY-W634748).
    3-Hydroxy desalkylgidazepam
  • HY-W717548
    Safinamide acid
    Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples.
    Safinamide acid
  • HY-W335576
    3-(Methylphosphinico)propionic acid
    3-(Methylphosphinico)propionic acid serves as a metabolite of the pesticide glufosinate ammonium.
    3-(Methylphosphinico)propionic acid
  • HY-101433R
    N-Acetylprocainamide hydrochloride (Standard)
    N-Acetylprocainamide (hydrochloride) (Standard) is the analytical standard of N-Acetylprocainamide (hydrochloride). This product is intended for research and analytical applications. N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K+ channels.
    N-Acetylprocainamide hydrochloride (Standard)
  • HY-174298
    Ipriflavone metabolites IV
    Ipriflavone metabolites IV is a metabolite of Ipriflavone (HY-N0094).
    Ipriflavone metabolites IV
  • HY-126194
    Tolcapone 3-β-D-glucuronide
    Tolcapone 3-β-D-glucuronide (Ro 61-1448) is an O-methyl metabolite and the glucuronide metabolite of Tolcapone (Ro 40-7592; HY-17406). Tolcapone 3-β-D-glucuronide is pharmacologically inactive.
    Tolcapone 3-β-D-glucuronide
  • HY-B0794S
    AZ7550-d5
    AZ7550-d5 is the deuterium labeled AZ7550?(HY-B0794). AZ7550, an active metabolite of Osimtinib (AZD9291; HY-15772), inhibits the activity of?IGF1R?with an?IC50?of 1.6 μM.
    AZ7550-d<sub>5</sub>
  • HY-123001
    Nomelidine
    Nomelidine is the metabolite of Zimelidine (HY-118835), that exhibits antidepressant and analgesic properties.
    Nomelidine
  • HY-150333
    MMB-ICA
    MMB-ICA is a metabolite of MMB-CHMICA.
    MMB-ICA
  • HY-W741106
    5-Hydroxybuspirone
    5-Hydroxybuspirone is a metabolite of the anti-anxiety agent Buspirone (HY-B1115A).
    5-Hydroxybuspirone
  • HY-124041
    p-Hydroxybestatin
    p-Hydroxybestatin is an active metabolite of Bestatinc (HY-B0134) that can be found in serum from muscular dystrophic patients and from healthy subjects dosed with Bestatin.
    p-Hydroxybestatin
  • HY-100583AR
    (±)-Equol (Standard)
    (±)-Equol (Standard) is the analytical standard of (±)-Equol. This product is intended for research and analytical applications. (±)-Equol is the racemate of equol. (±)-equol exhibits EC50s of 200 and 74 nM for human ERα and ERβ, respectively. Equol is a metabolite of the soy isoflavones, daidzin and daidzein.
    (±)-Equol (Standard)
  • HY-134999
    10-Hydroxywarfarin
    10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively.
    10-Hydroxywarfarin
  • HY-111811
    Homomangiferin
    Homomangiferin is mangiferin monomethyl ether. Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma.
    Homomangiferin
  • HY-B1986R
    p,p'-DDE (Standard)
    p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women.
    p,p'-DDE (Standard)
  • HY-W014993S1
    1,3-Dimethyluric acid-dsub>3
    1,3-Dimethyluric acid-d3 is deuterated labeled 1,3-Dimethyluric acid (HY-W014993). 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid-dsub>3</sub>
  • HY-W008614S1
    Lansoprazole sulfone-13C6
    Lansoprazole sulfone-13C6 (AG-1813-13C6) is 13C labeled Lansoprazole sulfone. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
    Lansoprazole sulfone-<sup>13</sup>C<sub>6</sub>
  • HY-116074
    FUB-PB-22 3-carboxyindole metabolite
    FUB-PB-22 3-carboxyindole metabolite is the main metabolite of FDU-PB-22 and FUB-PB-22.
    FUB-PB-22 3-carboxyindole metabolite
Cat. No. Product Name / Synonyms Application Reactivity